Schedule and News
- Paper accepted for publication "A Model for the Nonlinear Mechanism Responsible for Cochlear Amplification" (24 July 14)
- Assisted with MBI-CAMBAM-NIMBioS Summer Graduate Program at MBI (7-18 July 14)
- Attended Workshop on Diabetes Systems Biology at Fields Institute, Toronto (24-26 Mar 14)
- Presented poster at MBI Institute Partners Meeting titled "A Multiscale Examination of Nonlinear Waves in the Cochlea" (02 Feb 14)
- Email: fessel.6 (at) mbi.osu.edu
- Office: Jennings Hall 380,
Ohio State University
- Phone: 614.688.3334
- Postdoctoral Fellow at the Mathematical Biosciences Institute (September 2013 -- present)
- Ph. D. in Mathematics, Rensselaer Polytechnic Institute (May 2013)
- M. S. in Applied Mathematics, Rensselaer Polytechnic Institute (December 2009)
- B. S. in Applied Mathematics and Professional Chemistry, University of Evansville (May 2007)
I am primarily interested in mathematical biology, asymptotic methods, and combining analytics with numerics to arrive at system solutions. Below are brief descriptions of my current and recent research. (COMING SOON--Click the headers for more details on each project.)
- Cancer Cell Lineage
My current research focuses on the development of a cancer lineage model which includes the effect of radiation-induced cellular de-differentiation. A coupled ODE population model is used to track stem, committed progenitor, and differentiation cells both with and without applied radiation, and the role of various internal feedbacks is under investigation.
- Glucose-Insulin Dynamics
I am also currently analyzing glucose-insulin interactions via analytic solution to the Bergman-Cobelli Minimal Model. With the use of an expanded intermediary function, we have developed a constrained minimizing algorithm to fit patient-specific parameters for diabetes prediction. We are now testing this analytic-numeric approach on clinical data.
- Active Hearing
My thesis research centered around the development of a comprehensive model for the transduction mechanism of the mammalian cochlea. The fluid-solid interactions of the cochlea can be described by coupled PDEs; whereas, a micromechanical model has been developed to represent the outer hair cells' external forcing which influences the system nonlinearly.
A PDF copy of my CV can be found here.
Last update: 08 July 2014.