JOURNAL CLUB ON MODELS OF CELL-FATE REGULATION

Cell Death

    Introductory lecture, Apoptosis Model
    A molecular basis set for cytokine-induced apoptosis

Cell Cycle

  Introductory lecture, Cell Cycle Models
  Eukaryotic Cell Cycle, Yeast and Bacteria
  Cell Cycle Checkpoints
  Spindle Checkpoint  

  Coupling of Signaling, Cell Cycle and Apoptosis  

Cell Differentiation

  Introductory lecture, Gene networks, T Lymphocyte Model
  Th1 and Th2 Differentiation
  High-dimensional switches  

  

Cell Maintenance, Aging and Renewal

  Introductory lecture, Senescence, Aging, DNA damage repair
  Maintenance of vascular endothelial wall
  A dynamic model of hematopoietic stem cell organization  


Abnormal Cell-Fate Regulation (Cancer)

   Hallmarks of Cancer
   Multiscale colorectal cancer model
   Multiscale model of avascular tumor spheroids  

   Review of multiscale models of avascular tumors  
   Nonlinear simulation of tumor growth  

 

JOURNAL CLUB ON MODELS OF TUMOR IMMUNOLOGY & INFLAMMATION


  Immunity to infection with M. tuberculosis
  Reduced model of acute inflammation

  Modeling Systems-Level Regulation of Host Immune Responses (paper of Thakar et al., 2007)